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BRAIN MECHANISMS OF OVEREATING : HOW DO HIGH-CALORIE FOODS INFLUENCE THE
BRAIN?
Dr. Anastasia Dimitropoulos at Case Western Reserve University is seeking
persons with PWS 18-40 years of age to come participate in Cleveland, OH.
The purpose of this research is to use functional Magnetic Resonance Imaging
(fMRI) to understand what happens in the brain when people with Prader-Willi
syndrome think about different types of food. fMRI is a noninvasive brain scan
during which participants will view pictures of different types of food and
objects. We aim to identify whether the brain responds differently to
high-calorie foods when people with PWS have not eaten for several hours
compared to after eating. Ultimately, we hope to understand what role rewarding
food has on the eating disorder in PWS. The information gained from this study
may facilitate the development of appropriate interventions for the overeating
problem and food-related preoccupations in Prader-Willi syndrome.
Participation Requirements:
- Individuals 18-40 years of age
- Must have genetic diagnosis of PWS
- Capable of having MRI scan (email for eligibility criteria: axd116@case.edu)
Participation involves a 1-day visit to CWRU (Cleveland, OH), featuring:
- Functional MRI scan
- Cognitive assessment
- Food preference survey
Participants receive an honorarium to help defray the costs incurred for time
and travel. Parking costs are reimbursed. Lunch is provided prior to the fMRI
scan. To schedule a date to participant or to find out more information, please
contact Anastasia Dimitropoulos at
axd116@case.edu or 216-368-3471 or visit the lab website:
http://www.case.edu/artsci/pscl/dimitropoulos/index.html.
This work is supported by grant RO3HD058766-01 from the National Institute of
Child Health and Human Development.
Edited:
03/23/2010
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